Bevacizumab in advanced cancer, too much or too little?
نویسندگان
چکیده
منابع مشابه
Too much or too little
The global effort to understand the molecular drivers of cancer onset and progression is now coming to fruition with the identification of specific genomic and epigenomic events that influence signaling through key oncogenic pathways. Genetic studies using inducible expression of the critical growth controlling oncogenes MYC, RAS, PI3K and AKT have shown unequivocally that, in conjunction with ...
متن کاملRingler Too much or too little water in the Mekong ?
Prof. Andreas Wimmer Director at ZEF Since the end of the cold war, the development policy debate has undergone a remarkable transformation. Whereas before, the political and legal environment of a developing country has been scarcely taken into consideration, today human rights, good governance, the rule of law and democracy, peaceful conflict settlement etc. have become central elements of de...
متن کاملAntibiotics in intensive care: too little or too much?
T he article by Fragou et al (1), in this month’s Critical Care Medicine, provides compelling evidence that the routine use of ultrasound guidance increases the safety of central venous access by the subclavian route. In this cohort of critical care patients, cannulation was achieved in 100% of patients in the ultrasound group as compared with 87.5% in the landmark arm. Access time and the numb...
متن کاملNoradrenergic function and depression, too much or too little?
Antithetical hypotheses as to CNS noradrenergic function in depressed patients can be constructed from results of pharmacological studies of the effects of antidepressant drugs. The experimental data supporting each of these opposing propositions is briefly reviewed in this paper. Finally, the results of clinical studies of noradrenergic function in depressed patients are noted and discussed in...
متن کاملCorticosteroids and Asthma: Too Much or Too Little?
In this issue of Pediatrics, Farber et al1 present the results of an analysis of claims data for children with asthma who were enrolled in a large managed care Medicaid and Children’s Health Insurance Program from 2011 to 2016. During each of the years analyzed, 42.1% to 44.2% of the children had ≥1 event in which an oral corticosteroid (OCS) for asthma was dispensed. This frequency of OCS-disp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2008
ISSN: 0923-7534
DOI: 10.1093/annonc/mdn564